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Distributed Computing under Linux page (在Linux下分布式计算页面)
Distributed Computing under
Linux
Lars Lindbom and E. Niclas Jonsson
Division of Pharmacokinetics and Drug Therapy
Department of Pharmaceutical Biosciences
Uppsala University
Overview
• What is Distributed Computing?
– Enabling distributed computation
• What are the potential benefits of DC in
population PK/PD?
– Example
• Bootstrap
• Example of a small cluster
• Conclusions
What is Distributed Computing?
• It is using two workstations to solve one task
and gaining 100% in speed
• It is using 1000 processors (CPUs) to solve a
task that otherwise would have been
(practically) impossible to solve.
• It is using available resources more effeciently
Enabling Distributed Computation
Hardware Personal
Network
Computers
Fileserver,
Operating Tape backup
System
Cluster
Computing Nodes
Methods
(Software)
Enabling distributed computation
There is more to distributed computing than
connecting computers to a common network
Hardware
Operating • Making the computing nodes talk to each other
System and cooperate
Methods • Identifying the parts of a scientific problem that
(Software) can be parallelized
What are the potential benefits of
DC in population PK/PD?
• We rely on computers to fit models to data.
– Preferably, this task should be written for
the potential use of multiple processors
– No software support this today
• There are other tasks within a population
analy
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