Using DOE with Tolerance Intervals to Verify (用DOE宽容间隔来验证).pdfVIP

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Using DOE with Tolerance Intervals to Verify (用DOE宽容间隔来验证).pdf

Using DOE with Tolerance Intervals to Verify (用DOE宽容间隔来验证)

A Special Issue Article featuring a paper presented at 11th Annual ENBIS Conference Using DOE with Tolerance Intervals to Verify Specifications By Patrick J. Whitcomb and Mark J. Anderson (mark@) Given the push for Quality by Design (QbD) by the US FDA and equivalent agencies worldwide, statistical methods are becoming increasingly vital for pharmaceutical manufacturers. Design of experiments (DOE) is a primary tool because “it provides a structured, organized method for determining the relationship between factors affecting a 1 p

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