Changes in children with rotavirus enteritis serum and stool cytokine（轮状病毒肠炎患儿血清和粪便细胞因子的变化）.docVIP

Changes in children with rotavirus enteritis serum and stool cytokine [Keywords] rotavirus [Abstract] AIM: To explore the roles of cytokine interleukin8 (IL8) and tumor necrosis factorα (TNF @) in the pathogenesis of rotavirus (RV) enteritis and their clinical significance. METHODS: The levels of IL8 and TNF @ in the serum and stool of 46 children with RV enteritis were detected by the doubleantibody sandwich ELISA technique. RESULTS: The levels of IL8 and TNF @ in the serum and stool of children with RV enteritis at the acute phase were significantly higher than those in control group (P