a noninvasive mucinous cystic neoplasm with intermediate-grade dysplasia of the pancreas and extensive squamous metaplasia a case report with clinicopathological correlation一种非侵入性胰腺粘液性囊性肿瘤的中档发育不良的和广泛的鳞状上皮化生病例报告与临床病理的相关性.pdfVIP

Li et al. Diagnostic Pathology 2012, 7:89 /content/7/1/89 CASE REPORT Open Access A noninvasive mucinous cystic neoplasm with intermediate-grade dysplasia of the pancreas and extensive squamous metaplasia: a case report with clinicopathological correlation 1,2† 1† 3 1 1 1* Peifeng Li , Yingmei Wang , Qingqing Zhang , Yixiong Liu , Yang Lv and Zhe Wang Abstract: Squamous metaplasia presenting in noninvasive mucinous cystic neoplasm (MCN) of the pancreas is extremely rare. We described a case of 39-year-old Chinese female with a 5-year history of a slow growing mass in the left upper abdomen and an 18-month history of surgical incision exudation. The patient underwent cystojejunostomy, laparotomy and distal pancreatectomy consecutively because of the initial diagnosis of “pancreatic cyst”. The histological section showed columnar mucin-producing epithelium formed small papillary projections and extensively visible squamous metaplasia. Therefore the diagnosis of “noninvasive MCN with intermediate-grade dysplasia of the pancreas and extensive squamous metaplasia” was made finally. The squamous component of the pancreas may be derived from pluripotent stem cells, and may be in association with cystojejunostomy. Virtual slides: The virtual slide(s) for this article can be found here http://www.diagnosticpathology.diagnomx.eu/ vs/1322364365718540 Keywords: Mucinous cystic neoplasm, Squamous metaplasia, Pancreas, Immunohistochemistry Background extensive squamous metaplasia. In addition, we discuss the Mucinous cystic neoplasm (MCN) is a rare exocrine pathogenesis of squamous metaplasia and its clinicopatho- pancreatic tum