comparison of prevalence of metabolic syndrome in hospital and community-based japanese patients with schizophrenia代谢综合征患病率的比较日本精神分裂症患者在医院和社区.pdfVIP

Sugawara et al. Annals of General Psychiatry 2011, 10:21 /content/10/1/21 PRIMARY RESEARCH Open Access Comparison of prevalence of metabolic syndrome in hospital and community-based Japanese patients with schizophrenia 1,2* 2 1,2 3,4 5,6 2 Norio Sugawara , Norio Yasui-Furukori , Yasushi Sato , Ikuko Kishida , Hakuei Yamashita , Manabu Saito , Hanako Furukori7, Taku Nakagami2,8, Mitsunori Hatakeyama9 and Sunao Kaneko2 Abstract Background: Lifestyle factors, such as an unbalanced diet and lack of physical activity, may affect the prevalence of metabolic syndrome (MetS) in schizophrenic patients. The aim of this study was to compare the MetS prevalence between inpatients and outpatients among schizophrenic population in Japan. Methods: We recruited inpatients (n = 759) and outpatients (n = 427) with a Diagnostic and Statistical Manual of Mental Disorders, fourth edition (DSM-IV) diagnosis of schizophrenia or schizoaffective disorder from 7 psychiatric hospitals using a cross-sectional design. MetS prevalence was assessed using three different definitions, including the adapted National Cholesterol Education Program Adult Treatment Panel (ATP III-A). Results: The overall MetS prevalences based on the ATP III-A definition were 15.8% in inpatients and 48.1% in outpatients. In a logistic regression model with age and body mass index as covariates, being a schizophrenic outpatient, compared to being a schizophrenic inpatient, was a significant independent factor (odds ratio = 3.66 for males, 2.48 for females) in the development of MetS under the ATP III-A definition. The difference in MetS prevalence between inpatients and outpatients was observed for all age groups in males and for fe