conference highlights of the 5th international workshop on hiv persistence during therapy, 6-9 december 2011, st. maartin, west indies会议强调了第五届国际研讨会在治疗艾滋病毒的持久性,6 - 9 2011年12月,圣maartin,西印度群岛.pdfVIP

Stevenson et al. AIDS Research and Therapy 2012, 9:7 /content/9/1/7 REVIEW Open Access Conference highlights of the 5th international workshop on HIV persistence during therapy, 6-9 December 2011, St. Maartin, West Indies Mario Stevenson1†, Nicolas Chomont2† and Alain Lafeuillade3*† Abstract The December 2011 5th International Workshop on HIV Persistence during Therapy addressed the issue of HIV persistence among 210 scientists from 10 countries involved in the study of HIV reservoirs and the search of an HIV cure. High quality abstracts were selected and discussed as oral or poster presentations. The aim of this review is to distribute the scientific highlights of this workshop outside the group as analyzed and represented by experts in retrovirology, immunology and clinical research. Keywords: HIV persistence, HIV reservoirs, HIV latency, HIV cure, HIV eradication, HIV reservoir group Introduction Virology of HIV persistence The 5th international workshop on HIV persistence dur- Models of HIV latency ing therapy was held in St. Maarten from December 6-9 The development of strategies to eliminate HIV-1 reser- and featured presentations from 210 scientists repre- voirs that persist in the face of ART will require a com- senting approximately 10 countries. Since its inception, plete understanding of the nature of viral persistence and the goal of the workshop has been to provide a forum latency and how these processes are regulated. While for research aimed at understanding the mechanism by latency is considered the single biggest obstacle to viral which HIV-1 persists in the face of antiret