a risk-factor guided approach to reducing lactic acidosis and hyperlactatemia in patients on antiretroviral therapy一个因素引导的方法来减少乳酸酸中毒和hyperlactatemia抗逆转录病毒治疗的病人.pdfVIP

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a risk-factor guided approach to reducing lactic acidosis and hyperlactatemia in patients on antiretroviral therapy一个因素引导的方法来减少乳酸酸中毒和hyperlactatemia抗逆转录病毒治疗的病人.pdf

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a risk-factor guided approach to reducing lactic acidosis and hyperlactatemia in patients on antiretroviral therapy一个因素引导的方法来减少乳酸酸中毒和hyperlactatemia抗逆转录病毒治疗的病人

A Risk-Factor Guided Approach to Reducing Lactic Acidosis and Hyperlactatemia in Patients on Antiretroviral Therapy 1 2 3 2 4 Lynn T. Matthews *, Janet Giddy , Musie Ghebremichael , Jane Hampton , Anthony J. Guarino , Aba 5 6 3 7 3,8 3,9,10 Ewusi , Emma Carver , Karen Axten , Meghan C. Geary , Rajesh T. Gandhi , David R. Bangsberg 1 Division of Infectious Disease, Beth Israel Deaconess Medical Center, Boston, Massachusetts, United States of America, 2 HIV Program, McCord Hospital, Durban, South Africa, 3 Ragon Institute of Massachusetts General Hospital, Massachusetts Institute of Technology, and Harvard University, Boston, Massachusetts, United States of America, 4 Institute of Health Professions, Massachusetts General Hospital, Boston, Massachusetts, United States of America, 5 Division of Internal Medicine, Harvard Vanguard Medical Associates, Boston, Massachusetts, United States of America, 6 Department of Emergency Medicine, University Hospital of Wales, Cardiff, Wales, 7 Albany Medical College, Albany, New York, United States of America, 8 Division of Infectious Disease, Massachusetts General Hospital, Boston, Massachusetts, United States of America, 9 Mbarara University of Science and Technology, Mbarara, Uganda, 10 Center for Global Health, Massachusetts General Hospital, Boston, Massachusetts, United States of America Abstract Background: Stavudine continues to be used in antiretroviral treatment (ART) regimens in many resource-limited settings. The use of zidovudine instead of stavudine in higher-risk patien