消痛清畅汤治疗慢性非细菌性前列腺炎盆底疼痛综合症的疗效观察.doc

消痛清畅汤治疗慢性非细菌性前列腺炎/盆底疼痛综合症的 疗效观察 李欣宇1 李向安2 1.重庆医科大学附属第一医院药剂科 重庆（4000） 摘要： 目的 观察消痛清畅汤治疗慢性非细菌性前列腺炎/盆底疼痛综合症（Chronic Nonbacterial Prostatitis, CNP；Chronic pelvic pain syndrome, CPPS，CNP/ CPPS）的临床疗效。 方法：选择经临床确诊的136例CNP/ CPPS患者，口服消痛清畅汤，3次/d,共6周。分别于治疗前后，行NIH-慢性前列腺炎症状指数（NIH-CPSI）评分、临床体征、前列腺按摩液（EPS）检查、B超前列腺检查等指标测定。 结果：按照要求完成治疗的136例患者，NIH-CPSI总评分在治疗前后分别为（28.4±4.6）分和（13.8±3.6）分，平均降低14.6分，两者比较，差异有统计学意义(P 0.01)；EPS中白细胞计数治疗前后分别为（23.9±2.3）个/HP和（7.1±2.2）个/HP，卵磷脂小体在治疗前后分别为（＋）和（＋＋＋）。治愈59例（43.4%）；有效63例（46.3%）；无效14例（10.3%）。总有效率为89.7%，未见不良反应发生。 结论：消痛清畅汤治疗CNP/ CPPS的临床疗效显著，安全可靠。在缓解患者的疼痛和不适，提高生活质量方面效果明显。 关键词：慢性非细菌性前列腺炎/盆底疼痛综合症； 药物疗法；中医； 消痛清畅汤 中图分类号：R 697.33 Clinical effect of Xiao Tong Qing Chang Tang on the treatment of Chronic Nonbacterial Prostatitis / Chronic pelvic pain syndrome Li Xin yu 1 Li Xiang An 2 Department of the First Affiliated Hospital of Chong Qing Medical University. 2.Family Plan Service Centre , Chuan Shan District of Sui Ning City, Si Chuan Province Abstract Objective To explore the effectiveness of Xiao Tong Chang Qing Tang on the treatment of Chronic Nonbacterial Prostatitis / Chronic pelvic pain syndrome. Methods A total of 136 Chronic Abacterial Prostatitis / Chronic pelvic pain syndrome patients whose disease course were at least 4 months were enrolled in this study. And they received a treatment of oral Xiao Tong Qing Chang Tang for 6 weeks (3 times per day). NIH-chronic prostatitis symptom index (NIH-CPSI)and counting leukocytes in expressed prostatic secretions (EPS)were applied to assess the effectiveness. Results 136 cases accomplished treatment on request. Overall scores of NIH-CPSI in 136 patients before and after treatment were （28.4±4.6）and（13.8±3.6）respectively, and the score decreased 14.6 averagely (P 0.01).The number of lecithin small body was (+) and (+++) respectively. After the treatment, 59 patients（43.4%）were cured, 63 patients（46.3%）effectiveness and 14 patients（10.3%）no effect. Total effective rate was 89.7%.The apparent side effect