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a cautionary tale of virus and disease病毒和疾病的一个发人警醒的故事
Weiss BMC Biology 2010, 8:124
/1741-7007/8/124
O P I N I O N Open Access
A cautionary tale of virus and disease
Robin A Weiss*
(irst developed against HIV) in the hope of clearing
Abstract
infection and their symptoms. Blood banks would have
The recent identiication of the gammaretrovirus XMRV to consider whether to screen donations for the impli-
and a second gammaretrovirus of a diferent subtype cated retroviruses. But before such steps could be
in chronic fatigue syndrome has aroused much justiied, it will be essential to perform truly blinded tests
interest, not least among suferers. However, it remains on cases and proper controls in several laboratories.
highly controversial whether the detection of these Profoundly disappointing as this would be for patients,
viruses represents true infection or laboratory artifacts. without such additional studies, laboratory artifacts
cannot be ruled out; also, with the signal exceptions of
HIV and human T-lymphotrophic virus, the history of
A year ago, Lombardi et al. [1] reported in Science the retroviral associations with human disease is not
detection of a retrovirus in 67% of persons sufering from
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