均匀设计法探究八角油β-环糊精包合物制备工艺.docVIP

均匀设计法探究八角油β-环糊精包合物制备工艺 　【摘要】 　　目的　研究β-环糊精对八角油的包合作用。方法 以挥发油包合率为指标，应用3因素6水平的均匀设计法，筛选出八角油包合物的最佳制备条件，即温度、研磨时间、样品与β-CD的比例。结果实验得出最佳条件：当温度为35.0℃，研磨时间为4.0 h，八角茴香油与β-CD的比例1∶13.0（ ml∶g）时，包合率为81.4%；红外测定包合作用是否完全。结论优选得到的工艺结果稳定可行。 【关键词】 八角油； β-环糊精； 包合物制备； 均匀设计 　　Abstract:ObjectiveTo study the inclusion complex of Star anise oil with β－cyclodextrin. Methods3 factors and 6 levels of conditions for the preparation of the inclusion complex were selected by the uniform design. The ratio of Star anise oil in the inclusion complex was used as criterion in these experiments. The inclusion complex was made by pestling method. ResultsThe best conditions of the inclusion complex were that: the ratio of Star anise oil and β-Cyclodextrin was 1:13.0(mL/g), and grinding for 4.0 hours at 35.0℃. The ratio of volatile oil in the inclusion complex was about 81.4%, and the inclusion complex was identified by IR. ConclusionThe optimized process is stable and highly efficient. 　　Key wordsStar anise oil；β-Cyclodextrin； Inclusion process；Uniform design Guangxi is a Chinese autonomous province, located in a subtropical zone, south west of China. In particular, it has extensive resources of different plants. Among them, there is a special and commercial product, essential oil, which is widely recognized. Essential oils are the volatile, fragrant substances residing in the flowers, fruits, leaves, and roots of many plants［1］.Most of them are a complex mixture of chemical constituents，including nitrogen and sulfur-containing molecules, aromatic chemicals, and terpenes． 　　The following oils are the most famous and are found in large quantity in Guangxi. Eucalyptus oi1 has been employed in ointments as a topical counter-irritant and together with menthol as an inhalation［1］.Star anise oil is the main product in the fruits of Illicium verum. The plant contains remarkable essential oil, which is used as flavoring and medicine to control caught［2］.The related content of trans-Cinnamaldehyde in Guangxi cinn