a developing country response to lavery et al. in global health research, is it legitimate to stop clinical trials early on account of their opportunity costs一个发展中国家应对拉威利et al。在全球卫生研究,它是合法的停止临床试验早期因机会成本.pdfVIP

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a developing country response to lavery et al. in global health research, is it legitimate to stop clinical trials early on account of their opportunity costs一个发展中国家应对拉威利et al。在全球卫生研究,它是合法的停止临床试验早期因机会成本.pdf

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a developing country response to lavery et al. in global health research, is it legitimate to stop clinical trials early on account of their opportunity costs一个发展中国家应对拉威利et al。在全球卫生研究,它是合法的停止临床试验早期因机会成本

BMC Medical Ethics BioMed Central Debate Open Access A developing country response to Lavery et al. In global health research, is it legitimate to stop clinical trials early on account of their opportunity costs? Douglas R Wassenaar*1,2 and Gita Ramjee3 Address: 1Biomedical Research Ethics Committee, University of KwaZulu-Natal, Durban, South Africa, 2South African Research Ethics Training Initiative (SARETI), University of KwaZulu-Natal, Pietermaritzburg, South Africa and 3HIV Prevention Research Unit, Medical Research Council, Durban, South Africa Email: Douglas R Wassenaar* - wassenaar@ukzn.ac.za; Gita Ramjee - Gita.Ramjee@mrc.ac.za * Corresponding author Published: 30 September 2009 Received: 7 August 2009 Accepted: 30 September 2009 BMC Medical Ethics 2009, 10:16 doi:10.1186/1472-6939-10-16 This article is available from: /1472-6939/10/16 © 2009 Wassenaar and Ramjee; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: A recent paper presents an argument and mechanism for the possible stopping of clinical trials early based on opportunity costs. Discussion: Although we agree that the costs and opportunity costs of clinical trials need to be reduced wherever possible, we raise concerns about the motivation and mechanism for stopping clinical trial