原创力文档a randomised controlled trial to assess the efficacy of laparoscopic uterosacral nerve ablation (luna) in the treatment of chronic pelvic pain the trial protocol [isrctn41196151]疗效的随机对照试验评估腹腔镜uterosacral神经消融(月神)治疗慢性骨盆疼痛试验协议(isrctn41196151).pdfVIP
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a randomised controlled trial to assess the efficacy of laparoscopic uterosacral nerve ablation (luna) in the treatment of chronic pelvic pain the trial protocol [isrctn41196151]疗效的随机对照试验评估腹腔镜uterosacral神经消融(月神)治疗慢性骨盆疼痛试验协议(isrctn41196151)
BMC Womens Health BioMed Central
Study protocol Open Access
A randomised controlled trial to assess the efficacy of Laparoscopic
Uterosacral Nerve Ablation (LUNA) in the treatment of chronic
pelvic pain: The trial protocol [ISRCT
The LUNA Trial Collaboration*
Address: Department of Obstetrics and Gynaecology, Birmingham Clinical Trials Unit and Department of Public Health and Epidemiology,
University of Birmingham B15 2TT, UK
Email: The LUNA Trial Collaboration* - pallavi.latthe@bwhct.nhs.uk
* Corresponding author
Published: 08 December 2003 Received: 24 July 2003
Accepted: 08 December 2003
BMC Womens Health 2003, 3:6
This article is available from: /1472-6874/3/6
© 2003 The LUNA Trial Collaboration; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are
permitted in all media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: Chronic pelvic pain is a common condition with a major impact on health-related
quality of life, work productivity and health care utilisation. The cause of the pain is not always
obvious as no pathology is seen in 40–60% of the cases. In the absence of pathology there is no
established treatment. The Lee-Frankenhauser sensory nerve plexuses and parasympathetic ganglia
in the uterosacral ligaments carry pain from the uterus, cervix and other pelvic structures.
Interruption of these nerve trunks by laparosco
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