a simulation study of the reaction of human heart to biphasic electrical shocks人类心脏的反应的模拟研究两相的电击.pdfVIP

BMC Cardiovascular Disorders BioMed Central Research article Open Access A simulation study of the reaction of human heart to biphasic electrical shocks lulia M Popp*, Gunnar Seemann* and Olaf Dössel* Address: Institute of Biomedical Engineering, University Karlsruhe(TH), Kaiserstr. 12, 76131, Germany Email: lulia M Popp* - ip@ibt.uni-karlsruhe.de; Gunnar Seemann* - gs@ibt.uni-karlsruhe.de; Olaf Dössel* - od@ibt.uni-karlsruhe.de * Corresponding authors Published: 22 June 2004 Received: 19 January 2004 Accepted: 22 June 2004 BMC Cardiovascular Disorders 2004, 4:9 doi:10.1186/1471-2261-4-9 This article is available from: /1471-2261/4/9 © 2004 Popp et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original URL. Abstract Background: This article presents a study, which examines the effects of biphasic electrical shocks on human ventricular tissue. The effects of this type of shock are not yet fully understood. Animal experiments showed the superiority of biphasic shocks over monophasic ones in defibrillation. A mathematical computer simulation can increase the knowledge of human heart behavior. Methods: The research presented in this article was done with different models representing a three-dimensional wedge of ventricular myocardium. The electrophysiology was described with Priebe-Beuckelmann model. The realis