a subset of morphologically distinct mammary myoepithelial cells lacks corresponding immunophenotypic markers的一个子集形态不同的乳腺肌上皮细胞缺乏相应的immunophenotypic标记.pdfVIP
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a subset of morphologically distinct mammary myoepithelial cells lacks corresponding immunophenotypic markers的一个子集形态不同的乳腺肌上皮细胞缺乏相应的immunophenotypic标记
Available online /content/5/5/R151
Research article Open Access
A subset of morphologically distinct mammary myoepithelial
cells lacks corresponding immunophenotypic markers
Roy R Zhang, Yan-Gao Man, Russell Vang, Jeffrey S Saenger, Ross Barner, Darren T Wheeler,
Chang Y Liang, Tuyethoa N Vinh and Gary L Bratthauer
Department of Gynecologic and Breast Pathology, Armed Forces Institute of Pathology, Washington, DC, USA
Corresponding author: Yan-Gao Man (e-mail: man@)
Received: 6 Jun 2003 Revisions requested: 30 Jun 2003 Revisions received: 4 Jul 2003 Accepted: 7 Jul 2003 Published: 24 Jul 2003
Breast Cancer Res 2003, 5:R151-R156 (DOI 10.1186/bcr635)
© 2003 Zhang et al., licensee BioMed Central Ltd (Print ISSN 1465-5411; Online ISSN 1465-542X). This is an Open Access article: verbatim
copying and redistribution of this article are permitted in all media for any purpose, provided this notice is preserved along with the articles original
URL.
Abstract
Introduction: Immunostaining for smooth muscle actin (SMA) chromogen. SMA-negative ME cells were re-examined for the
is commonly used to elucidate mammary myoepithelial (ME) expression of other markers.
cells, whose presence or absence is a reliable criterion for
differentiating in situ and invasive carcinomas. However, some
Results: SMA-negative ME cells in two cases also failed to
morphologically distinct ME cells fail to stain for SMA. This
display immunoreactivity for other markers, including calponin,
study intended to assess whet
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