原创力文档an analysis of the sargasso sea resource and the consequences for database composition马尾藻海资源的分析和数据库组成的后果.pdfVIP
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an analysis of the sargasso sea resource and the consequences for database composition马尾藻海资源的分析和数据库组成的后果
BMC Bioinformatics BioMed Central
Research article Open Access
An analysis of the Sargasso Sea resource and the consequences for
database composition
1 2 2
Michael L Tress* , Domenico Cozzetto , Anna Tramontano and
Alfonso Valencia 1
Address: 1Protein Design Group, CNB-CSIC, Calle Darwin, Cantoblanco 28049 Madrid, Spain and 2Department of Biochemical Sciences,
University La Sapienza Rome, Italy
Email: Michael L Tress* - mtress@cnio.es; Domenico Cozzetto - domenico.cozzetto@uniroma1.it;
Anna Tramontano - anna.tramontano@uniroma1 .it; Alfonso Valencia - avalencia@cnio.es
* Corresponding author
Published: 19 April 2006 Received: 22 December 2005
Accepted: 19 April 2006
BMC Bioinformatics 2006, 7:213 doi:10.1186/1471-2105-7-213
This article is available from: /1471-2105/7/213
© 2006 Tress et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The environmental sequencing of the Sargasso Sea has introduced a huge new
resource of genomic information. Unlike the protein sequences held in the current searchable
databases, the Sargasso Sea sequences originate from a single marine environment and have been
sequenced from species that are not easily obtaina
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