an un-commissioned randomized, placebo-controlled double-blind study to test the effect of deep sea fish oil as a pain reliever for dogs suffering from canine oa一个un-commissioned随机、安慰剂对照双盲测试的影响研究深海鱼油作为狗患犬oa的止痛药.pdfVIP

An un-commissioned randomized, placebo-controlled double-blind study to test the effect of deep sea fish oil as a pain reliever for dogs suffering from canine OA Hielm-Björkman et al. Hielm-Björkman et al. BMC Veterinary Research 2012, 8:157 /1746-6148/8/157 Hielm-Björkman et al. BMC Veterinary Research 2012, 8:157 /1746-6148/8/157 RESEARCH ARTICLE Open Access An un-commissioned randomized, placebo-controlled double-blind study to test the effect of deep sea fish oil as a pain reliever for dogs suffering from canine OA 1* 1,2 2 1 3 Anna Hielm-Björkman , Johanna Roine , Kari Elo , Anu Lappalainen , Jouni Junnila and Outi Laitinen-Vapaavuori1 Abstract Background: An un-commissioned randomized, double-blinded, placebo controlled clinical study was planned using a deep sea fish oil product for pets. Seventy-seven client-owned dogs with osteoarthritis were randomly assigned to supplement the food with either the fish oil product or corn (=placebo) oil. Our main outcome variables were force platform variables peak vertical force (PVF) and impulse, the validated Helsinki Chronic Pain Index (HCPI) and the use of rescue NSAIDs. Secondary outcome variables were a locomotion visual analog scale (VAS), a Quality of life VAS, a comparative questionnaire, a veterinary assessment, owners’ final assessment of outcome and guessing the product given. Results: When comparing the two test groups at the end of the trial (16 weeks) there was no significant difference in any of the main outcome variables but owners of dogs that had taken fish oil were significantly happier with the treatment at the end visit and