原创力文档an unusual association of diffuse adenomyomatosis with dysplastic adenoma in chronic calculous cholecystitis case presentation一个不寻常的漫射adenomyomatosis协会与发育异常的腺瘤在慢性结石性胆囊炎案例演示.pdfVIP
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an unusual association of diffuse adenomyomatosis with dysplastic adenoma in chronic calculous cholecystitis case presentation一个不寻常的漫射adenomyomatosis协会与发育异常的腺瘤在慢性结石性胆囊炎案例演示
Di Carlo et al. BMC Gastroenterology 2010, 10:41
/1471-230X/10/41
C A S E R E P O R T Open Access
Case report
An unusual association of diffuse
adenomyomatosis with dysplastic adenoma in
chronic calculous cholecystitis: case presentation
1 1 1 1 2
Isidoro Di Carlo* , Adriana Toro , Elia Pulvirenti , Monica Zisa and Antonio Galia
Abstract
Background: Gallbladder adenomyomatosis is an epithelial proliferation and hypertrophy of the muscularis mucosae
of the gallbladder. Rokitansky-Aschoff sinuses are a characteristic of this condition. The segmental adenomyomatosis
has a higher risk of developing into gallbladder carcinoma, especially in the fundal region of elderly patients.
We report the case of a patient affected by chronic calculous cholecystitis with diffuse adenomyomatosis associated
with dysplastic adenoma.
Case presentation: An 81-year-old woman presented at our hospital with a 1-year history of intermittent pain
localized at the right upper abdominal quadrant, without diffusion to any other body part. On physical examination
the abdomen was soft, not distended, and tender to palpation in the right upper quadrant. Murphy sign was negative.
Laboratory tests were normal. The patient was scheduled for a laparoscopic cholecystectomy, and neither endoscopic
ultrasonographic scan nor magnetic resonance imaging was performed. The operation, performed after obtaining
informed consent, was uncomplicated and the intra-operative pathological examination showed no malignancy. The
definitive pathological examination of the gallbladder showed: multiple stones of cholesterol origin; diffuse mucosal
adenomyomatosis; and a 1.1 cm pedunculated mass localized at the fundus, whose surface was lumpy. This mass was
diagnosed as an aden
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