原创力文档analysis of baseline and cisplatin-inducible gene expression in fanconi anemia cells using oligonucleotide-based microarrays分析基线和cisplatin-inducible使用oligonucleotide-based fanconi贫血细胞基因表达微阵列.pdfVIP
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analysis of baseline and cisplatin-inducible gene expression in fanconi anemia cells using oligonucleotide-based microarrays分析基线和cisplatin-inducible使用oligonucleotide-based fanconi贫血细胞基因表达微阵列
BMC Blood Disorders BioMed Central
BMC Blood Disorders x
2002, Open Access
2
Research article
Analysis of baseline and cisplatin-inducible gene expression in
Fanconi anemia cells using oligonucleotide-based microarrays
1 2 1 2
Quinten Waisfisz , Akira Miyazato , Johan P de Winter , Johnson M Liu and
Hans Joenje*1
Address: 1Department of Clinical Genetics and Human Genetics, VU University Medical Center, Amsterdam, The Netherlands and 2The
Hematology Branch, National Heart, Lung and Blood Institute, Bethesda, MD, USA
E-mail: Quinten Waisfisz - q.waisfisz.humgen@med.vu.nl; Akira Miyazato - amiya@jichi.ac.jp; Johan P de
Winter - j.de_winter.humgen@med.vu.nl; Johnson M Liu - Johnson.Liu@; Hans Joenje* - h.joenje.humgen@med.vu.nl
*Corresponding author
Published: 26 November 2002 Received: 3 October 2002
Accepted: 26 November 2002
BMC Blood Disorders 2002, 2:5
This article is available from: /1471-2326/2/5
© 2002 Waisfisz et al; licensee BioMed Central Ltd. This is an Open Access article: verbatim copying and redistribution of this article are permitted in all
media for any purpose, provided this notice is preserved along with the articles original URL.
Abstract
Background: Patients with Fanconi anemia (FA) suffer from multiple defects, most notably of the
hematological compartment (bone marrow failure), and susceptibility to cancer. Cells from FA
patients show increas
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