analysis of transitions at two-fold redundant sites in mammalian genomes. transition redundant approach-to-equilibrium (trex) distance metrics分析转换在哺乳动物基因组的双重冗余的网站。.pdfVIP
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analysis of transitions at two-fold redundant sites in mammalian genomes. transition redundant approach-to-equilibrium (trex) distance metrics分析转换在哺乳动物基因组的双重冗余的网站。
BMC Evolutionary Biology BioMed Central
Research article Open Access
Analysis of transitions at two-fold redundant sites in mammalian
genomes. Transition redundant approach-to-equilibrium (TREx)
distance metrics
†1 †1 1 2
Tang Li , Stephen G Chamberlin , M Daniel Caraco , David A Liberles ,
1 †1
Eric A Gaucher and Steven A Benner*
Address: 1Foundation for Applied Molecular Evolution, Gainesville FL 32604, USA and 2Department of Molecular Biology, University of
Wyoming, Laramie, WY 82071, USA
Email: Tang Li - tli@; Stephen G Chamberlin - schamberlin@; M Daniel Caraco - daniel@caraco.ch;
David A Liberles - liberles@; Eric A Gaucher - egaucher@; Steven A Benner* - sbenner@
* Corresponding author †Equal contributors
Published: 20 March 2006 Received: 03 August 2005
Accepted: 20 March 2006
BMC Evolutionary Biology2006, 6:25 doi:10.1186/1471-2148-6-25
This article is available from: /1471-2148/6/25
© 2006Li et al; licensee BioMed Central Ltd.
This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0),
which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited.
Abstract
Background: The exchange of nucleotides at synonymous sites in a gene encoding a protein is
believed to have little impact on the
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