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association of alpha1a-adrenergic receptor polymorphism and blood pressure phenotypes in the brazilian population协会alpha1a-adrenergic受体多态性和血压表型在巴西人口.pdfVIP

association of alpha1a-adrenergic receptor polymorphism and blood pressure phenotypes in the brazilian population协会alpha1a-adrenergic受体多态性和血压表型在巴西人口.pdf

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association of alpha1a-adrenergic receptor polymorphism and blood pressure phenotypes in the brazilian population协会alpha1a-adrenergic受体多态性和血压表型在巴西人口

BMC Cardiovascular Disorders BioMed Central Research article Open Access Association of alpha1a-adrenergic receptor polymorphism and blood pressure phenotypes in the Brazilian population 1,2 1 1 3 Silvia R Freitas , Alexandre C Pereira* , Marcilene S Floriano , José G Mill and José E Krieger1 Address: 1Laboratory of Genetics and Molecular Cardiology, Heart Institute/InCor, University of São Paulo Medical School, São Paulo, Brazil, 2Laboratory of Human Genetics, Oswaldo Cruz Institute/FIOCRUZ, Rio de Janeiro, Brazil and 3Department of Physiology, Espírito Santo Federal University, Vitória, Brazil Email: Silvia R Freitas - sroig@ioc.fiocruz.br; Alexandre C Pereira* - alexandre.pereira@incor.usp.br; Marcilene S Floriano - marcilene.floriano@incor.usp.br; José G Mill - jgmill@npd.ufes.br; José E Krieger - krieger@incor.usp.br * Corresponding author Published: 23 December 2008 Received: 1 September 2008 Accepted: 23 December 2008 BMC Cardiovascular Disorders 2008, 8:40 doi:10.1186/1471-2261-8-40 This article is available from: /1471-2261/8/40 © 2008 Freitas et al; licensee BioMed Central Ltd. This is an Open Access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Background: The alpha1A-adrenergic receptor (α -AR) regulates the cardiac and per

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