assembling proteomics data as a prerequisite for the analysis of large scale experiments组装蛋白质组学数据作为一个大型实验的分析的先决条件.pdfVIP

Chemistry Central Journal Research article Open Access Assembling proteomics data as a prerequisite for the analysis of large scale experiments 1,4 1 2 3 Frank Schmidt* , Monika Schmid , Bernd Thiede , Klaus-Peter Pleißner , 3 1 Martina Böhme and Peter R Jungblut Address: 1Max Planck Institute for Infection Biology, Core Facility Protein Analysis, Berlin, Germany, 2The Biotechnology Centre of Oslo, University of Oslo, Oslo, Norway, 3Max Planck Institute for Infection Biology, Core Facility Bioinformatics, Berlin, Germany and 4Interfaculty Institute for Genetics and Functional Genomics, University of Greifswald, Greifswald, Germany Email: Frank Schmidt* - Frank.Schmidt@uni-greifswald.de; Monika Schmid - Schmid@mpiib-berlin.mpg.de; Bernd Thiede - Bernd.Thiede@biotek.uio.no; Klaus-Peter Pleißner - pleissner@mpiib-berlin.mpg.de; Martina Böhme - Boehme@mpiib- berlin.mpg.de; Peter R Jungblut - jungblut@mpiib-berlin.mpg.de * Corresponding author Published: 23 January 2009 Received: 10 October 2008 Accepted: 23 January 2009 Chemistry Central Journal 2009, 3:2 doi:10.1186/1752-153X-3-2 This article is available from: /content/3/1/2 © 2009 Schmidt et al Abstract Background: Despite the complete determination of the genome sequence of a huge number of bacteria, their proteomes remain relatively poorly defined. Beside new methods to increase the number of identified proteins new database applications are necessary to store and present results of large- scale proteomics experimen