association of health behaviour with heart rate variability a population-based study协会健康行为与心率变异性以人群为基础的研究.pdfVIP

Kluttig et al. BMC Cardiovascular Disorders 2010, 10:58 /1471-2261/10/58 RESEARCH ARTICLE Open Access Association of health behaviour with heart rate variability: a population-based study 1* 1,2 3 4 1 5 Alexander Kluttig , Barbara Schumann , Cees A Swenne , Jan A Kors , Oliver Kuss , Hendrik Schmidt , 6 1 1,7 Karl Werdan , Johannes Haerting , Karin H Greiser Abstract Background: Reduced heart rate variability (HRV), a non-invasive marker of autonomic dysfunction, and an unhealthy lifestyle are associated with an increased morbidity and mortality of cardiovascular diseases (CVD). The autonomic dysfunction is a potential mediator of the association of behavioural risk factors with adverse health outcomes. We studied the association of HRV with behavioural risk factors in an elderly population. Methods: This analysis was based on the cross-sectional data of 1671 participants (age range, 45-83 years) of the prospective, population-based Cardiovascular Disease, Living and Ageing in Halle (CARLA) Study. Physical activity, smoking habits, alcohol consumption and dietary patterns were assessed in standardized interviews. Time and frequency domain measures of HRV were computed from 5-min segments of highly standardized 20-min electrocardiograms. Their association with behavioural risk factors was determined by linear and non-parametric regression modelling. Results: There were only weak and inconsistent associations of higher physical activity, moderate consumption of alcohol, and non-smoking with higher time and frequency domain HRV in both sexes, and no association with dietary pattern. Results changed only marginally by ex