predictors of extra care among magnesium sulphate treated eclamptic patients at muhimbili national hospital, tanzania预测中格外小心硫酸镁治疗惊厥的病人muhimbili国立医院,坦桑尼亚.pdfVIP
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predictors of extra care among magnesium sulphate treated eclamptic patients at muhimbili national hospital, tanzania预测中格外小心硫酸镁治疗惊厥的病人muhimbili国立医院,坦桑尼亚
Muganyizi and Shagdara BMC Pregnancy and Childbirth 2011, 11:41
/1471-2393/11/41
RESEARCH ARTICLE Open Access
Predictors of extra care among magnesium
sulphate treated eclamptic patients at Muhimbili
National Hospital, Tanzania
Projestine S Muganyizi1* and Mohammed S Shagdara2
Abstract
Background: The inclusion of Magnesium Sulphate (MgSO4) as a gold standard in the treatment of eclampsia has
substantially reduced incidences of repeated fits, eclamptic morbidity and deaths. However, despite treatment with
MgSO4, a proportion of patients need extra medical/nursing attention and prolonged stay in the intensive care
unit (ICU). The literature on the underlying factors for the need of extra care in the MgSO4 era is lacking. This
study sought to establish predictors of extra care in ICU among eclamptic patients after treatment with MgSO4 at
Muhimbili National Hospital (MNH).
Methods: Data were obtained from hospital records of eclamptic patients who were admitted at MNH and treated
with MgSO4 from January 1st to December 31st, 2008. Based on set criteria, patients who needed extra care were
identified. Analysis was performed using PASW statistics 18 whereby frequencies, cross-tabulations, bivariate and
multiple logistic regressions were performed.
Results: A total of 366 eclamptic patients were admitted and treated with MgSO4 at MNH during a 12 month
study period in 2008. Most of these (76%) were referred from district hospitals and132 (36%) met the criteria for
extra care in ICU. After adjusting for other variables, the risk of extra care in ICU for patients who were admitted
with altered consciousness was double (OR = 2.3; 95% CI: 1.3-4.0) that of the ones admitted in alert state. The risk
or need of extra care increased by increasing time to delivery and was doubled (OR = 2.0; 95% CI:1.1-3.7) if it was
between
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