prevalence of attention deficit hyperactivity disorder among children and adolescents in spain a systematic review and meta-analysis of epidemiological studies注意缺陷多动障碍儿童和青少年患病率在西班牙流行病学研究的系统回顾和荟萃分析.pdfVIP
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prevalence of attention deficit hyperactivity disorder among children and adolescents in spain a systematic review and meta-analysis of epidemiological studies注意缺陷多动障碍儿童和青少年患病率在西班牙流行病学研究的系统回顾和荟萃分析
Catalá-López et al. BMC Psychiatry 2012, 12:168
/1471-244X/12/168
RESEARCH ARTICLE Open Access
Prevalence of attention deficit hyperactivity
disorder among children and adolescents in
Spain: a systematic review and meta-analysis
of epidemiological studies
1,2* 1,2 1,3 1 4
Ferrán Catalá-López , Salvador Peiró , Manuel Ridao , Gabriel Sanfélix-Gimeno , Ricard Gènova-Maleras
and Miguel A Catalá5
Abstract
Background: Attention deficit hyperactivity disorder (ADHD) is a commonly diagnosed neuropsychiatric disorder in
childhood, but the frequency of the condition is not well established in many countries. The aim of the present
study was to quantify the overall prevalence of ADHD among children and adolescents in Spain by means of a
systematic review and meta-analysis.
Methods: PubMed/MEDLINE, IME, IBECS and TESEO were comprehensively searched. Original reports were selected
if they provided data on prevalence estimates of ADHD among people under 18 years old in Spain and were cross-
sectional, observational epidemiological studies. Information from included studies was systematically extracted and
evaluated. Overall pooled-prevalence estimates of ADHD were calculated using random-effects models. Sources of
heterogeneity were explored by means sub-groups analyses and univariate meta-regressions.
Results: Fourteen epidemiological studies (13,026 subjects) were selected. The overall pooled-prevalence of ADHD
was estimated at 6.8% [95% confidence interval (CI) 4.9 – 8.8%] representing 361,580 (95% CI 260,550 – 467,927)
children and adolescents in the community. There was significant heterogeneity (P 0.001), which was
incompletely explained by subgroup analyses and meta-regressions.
Conclus
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