randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients随机试验比较日常中断镇静和nursing-implemented镇静算法在医学重症监护室的病人.pdfVIP

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randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients随机试验比较日常中断镇静和nursing-implemented镇静算法在医学重症监护室的病人.pdf

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Available online /content/12/3/R70 Vol 12 No 3 Open Access Research Randomized trial comparing daily interruption of sedation and nursing-implemented sedation algorithm in medical intensive care unit patients 1 2 1 3 Marjolein de Wit , Chris Gennings , Wendy I Jenvey and Scott K Epstein 1Pulmonary and Critical Care Division, Department of Internal Medicine, School of Medicine, Virginia Commonwealth University, PO Box 980050, Richmond, VA 23298-0050, USA 2Department of Biostatistics, School of Medicine, Virginia Commonwealth University, Box 980032, Richmond, VA, USA 3Tufts University School of Medicine, 145 Harrison Street, Boston, MA 02111, USA Corresponding author: Marjolein de Wit, mdewit@ Received: 1 May 2008 Revisions requested: 6 May 2008 Revisions received: 13 May 2008 Accepted: 20 May 2008 Published: 20 May 2008 Critical Care 2008, 12:R70 (doi:10.1186/cc6908) This article is online at: /content/12/3/R70 © 2008 de Wit et al.; licensee BioMed Central Ltd. This is an open access article distributed under the terms of the Creative Commons Attribution License (/licenses/by/2.0), which permits unrestricted use, distribution, and reproduction in any medium, provided the original work is properly cited. Abstract Introduction Daily interruption of sedation (DIS) and sedation analysis demonstrated a significant difference in primary algorithms (SAs) have been shown to decrease mechanical endpoint, and study termination was recommended. The DIS ventilation (MV) duration. We conducted a randomized study group had longer to