sublingual misoprostol versus standard surgical care for treatment of incomplete abortion in five sub-saharan african countries舌下米索前列醇与标准不完全流产的手术护理治疗五个撒哈拉以南非洲国家.pdfVIP
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sublingual misoprostol versus standard surgical care for treatment of incomplete abortion in five sub-saharan african countries舌下米索前列醇与标准不完全流产的手术护理治疗五个撒哈拉以南非洲国家
Shochet et al. BMC Pregnancy and Childbirth 2012, 12:127
/1471-2393/12/127
RESEARCH ARTICLE Open Access
Sublingual misoprostol versus standard surgical
care for treatment of incomplete abortion in five
sub-Saharan African countries
1 1* 2 3 4 5 6
Tara Shochet , Ayisha Diop , Alioune Gaye , Madi Nayama , Aissata Bal Sall , Fawole Bukola , Thieba Blandine ,
5 7 5 1
Okunlola Michael Abiola , Blami Dao , Ogunbode Olayinka and Beverly Winikoff
Abstract
Background: In low-resource settings, where abortion is highly restricted and self-induced abortions are common,
access to post-abortion care (PAC) services, especially treatment of incomplete terminations, is a priority. Standard
post-abortion care has involved surgical intervention but can be hard to access in these areas. Misoprostol provides
an alternative to surgical intervention that could increase access to abortion care. We sought to gather additional
evidence regarding the efficacy of 400 mcg of sublingual misoprostol vs. standard surgical care for treatment of
incomplete abortion in the environments where need for economical non-surgical treatments may be most useful.
Methods: A total of 860 women received either sublingual misoprostol or standard surgical care for treatment of
incomplete abortion in a multi-site randomized trial. Women with confirmed incomplete abortion, defined as past
or present history of vaginal bleeding during pregnancy and an open cervical os, were eligible to participate.
Participants returned for follow-up one week later to confirm clinical status. If abortion was incomplete at that time,
women were offe
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