原创力文档subtype distribution of lymphomas in southwest china analysis of 6,382 cases using who classification in a single institution淋巴瘤的亚型分布在中国西南地区的分析6382例使用世卫组织分类在一个单一的机构.pdfVIP
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subtype distribution of lymphomas in southwest china analysis of 6,382 cases using who classification in a single institution淋巴瘤的亚型分布在中国西南地区的分析6382例使用世卫组织分类在一个单一的机构
Yang et al. Diagnostic Pathology 2011, 6:77
/content/6/1/77
RESEARCH Open Access
Subtype distribution of lymphomas in Southwest
China: Analysis of 6,382 cases using WHO
classification in a single institution
Qun-Pei Yang, Wen-Yan Zhang, Jian-Bo Yu, Sha Zhao, Huan Xu, Wei-Ya Wang, Cheng-Feng Bi, Zhuo Zuo,
*
Xiao-Qing Wang, Juan Huang, Lin Dai and Wei-Ping Liu
Abstract
Background: The subtype distribution of lymphoid neoplasms in Southwest China was analyzed according to
WHO classifications. This study aims to analyze subtype distribution of lymphomas in southwest China.
Methods: Lymphoid neoplasms diagnosed within 9 years in a single institution in Southwest China were analyzed
according to the WHO classification.
Results: From January 2000 to December 2008, a total number of 6,382 patients with lymphoma were established,
of which mature B-cell neoplasms accounted for 56%, mature T- and NK-cell neoplasms occupied 26%, and
precursor lymphoid neoplasms and Hodgkin lymphomas were 5% and 13%, respectively. Mixed cellularity (76%)
was the major subtype of classical Hodgkin lymphoma; and the bimodal age distribution was not observed. The
top six subtypes of non-Hodgkin lymphoma were as follows: diffuse large B-cell lymphoma, extranodal NK/T-cell
lymphoma, nasal type, extranodal marginal zone lymphoma of mucosa associated lymphoid tissue, follicular
lymphoma, precursor lymphoid neoplasms, and chronic lymphocytic leukemia/small lymphocytic lymphoma.
Extranodal lymphomas comprised about half of all cases, and most frequently involved Waldeyer’s ring,
gastrointestinal tract, sinonasal region and skin.
Conclusions: The lymphoid neoplasms of Southwest China displayed some epidemiologic features similar to those
reported in literature from western and
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