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analysis of the subunit stoichiometries in viral entry亚基的分析化学计量学在病毒进入
Analysis of the Subunit Stoichiometries in Viral Entry
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Carsten Magnus* , Roland R. Regoes
Integrative Biology, The Swiss Federal Institute of Technology, Zurich, Switzerland
Abstract
Virions of the Human Immunodeficiency Virus (HIV) infect cells by first attaching with their surface spikes to the CD4
receptor on target cells. This leads to conformational changes in the viral spikes, enabling the virus to engage a coreceptor,
commonly CCR5 or CXCR4, and consecutively to insert the fusion peptide into the cellular membra
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