deficiency of the mitochondrial electron transport chain in muscle does not cause insulin resistance缺乏线粒体电子传递链的肌肉不会导致胰岛素抵抗.pdfVIP

Deficiency of the Mitochondrial Electron Transport Chain in Muscle Does Not Cause Insulin Resistance Dong-Ho Han, Chad R. Hancock, Su Ryun Jung, Kazuhiko Higashida, Sang Hyun Kim, John O. Holloszy* Division of Geriatrics and Nutritional Sciences, Department of Medicine, Washington University School of Medicine, Saint Louis, Missouri, United States of America Abstract Background: It has been proposed that muscle insulin resistance in type 2 diabetes is due to a selective decrease in the components of the mitochondrial electron transport chain and results from accumulation