depletion of the c. elegans nac engages the unfolded protein response, resulting in increased chaperone expression and apoptosis损耗的秀丽隐杆线虫nac展开的蛋白质反应,导致增加伴侣蛋白表达和细胞凋亡.pdfVIP
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depletion of the c. elegans nac engages the unfolded protein response, resulting in increased chaperone expression and apoptosis损耗的秀丽隐杆线虫nac展开的蛋白质反应,导致增加伴侣蛋白表达和细胞凋亡
Depletion of the C. elegans NAC Engages the Unfolded
Protein Response, Resulting in Increased Chaperone
Expression and Apoptosis
Paul T. Arsenovic, Anthony T. Maldonado, Vaughn D. Colleluori, Tim A. Bloss*
Department of Biology, James Madison University, Harrisonburg, Virginia, United States of America
Abstract
The nascent polypeptide-associated complex (NAC) is a highly conserved heterodimer important for metazoan
development, but its molecular function is not well understood. Recent evidence suggests the NAC is
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