design constraints on a synthetic metabolism合成代谢设计约束.pdfVIP

Design Constraints on a Synthetic Metabolism Tugce Bilgin1,2*, Andreas Wagner1,2,3 ¨ 1 Institute of Evolutionary Biology and Environmental Sciences, University of Zurich, Zurich, Switzerland, 2 The Swiss Institute of Bioinformatics, Zurich, Switzerland, 3 The Santa Fe Institute, Santa Fe, New Mexico, United States of America Abstract A metabolism is a complex network of chemical reactions that converts sources of energy and chemical elements into biomass