differential role of axin rgs domain function in wnt signaling during anteroposterior patterning and maternal axis formation轴蛋白该域函数的微分作用在wnt信号前后的模式和孕产妇轴形成.pdfVIP

Differential Role of Axin RGS Domain Function in Wnt Signaling during Anteroposterior Patterning and Maternal Axis Formation ¤ Patricia N. Schneider , Diane C. Slusarski, Douglas W. Houston* Interdisciplinary Graduate Program in Genetics, Department of Biology, University of Iowa, Iowa City, Iowa, United States of America Abstract Axin is a critical component of the b-catenin destruction complex and is also necessary for Wnt signaling initiation at the level of co-receptor activation. Axin contains an RGS domain, which is similar to th