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dimeric 2g12 as a potent protection against hiv-1二聚的2 g12作为一种有效的预防hiv - 1
Dimeric 2G12 as a Potent Protection against HIV-1
Xin M. Luo, Margarida Y. Y. Lei, Rana A. Feidi, Anthony P. West Jr., Alejandro Benjamin Balazs, Pamela J.
Bjorkman, Lili Yang*, David Baltimore*
Division of Biology, California Institute of Technology, Pasadena, California, United States of America
Abstract
We previously showed that broadly neutralizing anti-HIV-1 antibody 2G12 (human IgG1) naturally forms dimers that are
more potent than monomeric 2G12 in in vitro neutralization of various strains of HIV-1. In this study, we have investigated
the protective effe
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