direct engagement of tlr4 in invariant nkt cells regulates immune diseases by differential il-4 and ifn-γ production in mice直接接触的tlr4不变nkt细胞调节免疫疾病的微分小鼠il - 4和ifn-γ生产.pdfVIP

Direct Engagement of TLR4 in Invariant NKT Cells Regulates Immune Diseases by Differential IL-4 and IFN-c Production in Mice Ji Hyung Kim1,2.¤a, Hye Sung Kim1,2., Hye Young Kim 1¤b, Sae Jin Oh1,2, Doo Hyun Chung1,2* 1 Department of Pathology, Seoul National University College of Medicine, Seoul, Korea, 2 Laboratory of Immune Regulation in Department of Biomedical Sciences, Seoul National University College of Medicine, Seoul, Korea Abstract During interaction with APCs, invariant (i) NKT cells are thought to be indirectly activated by TLR4-dependently activated