distinct dna methylation dynamics of spermatogenic cell-specific intronless genes is associated with cpg content不同的精子发生的特异性dna甲基化动力学intronless基因与cpg相关内容.pdfVIP

Distinct DNA Methylation Dynamics of Spermatogenic Cell-Specific Intronless Genes Is Associated with CpG Content ¤ Yuzuru Kato , Masami Nozaki* Department of Cell Biology, Research Institute for Microbial Diseases, Osaka University, Suita, Osaka, Japan Abstract In mammals, DNA methylation is restricted to cytosines of CpG dinucleotides, which are frequently found in short genomic regions including gene promoters. Methylation within CpG-rich regions around promoters tends to repress gene expression; thus,