原创力文档dna display ii. genetic manipulation of combinatorial chemistry libraries for small-molecule evolutiondna显示二世。.pdfVIP
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dna display ii. genetic manipulation of combinatorial chemistry libraries for small-molecule evolutiondna显示二世。
PLoS BIOLOGY
DNA Display II. Genetic Manipulation
of Combinatorial Chemistry Libraries
for Small-Molecule Evolution
*
David R. Halpin, Pehr B. Harbury
Department of Biochemistry, Stanford University School of Medicine, Stanford, California, United States of America
Biological in vitro selection techniques, such as RNA aptamer methods and mRNA display, have proven to be powerful
approaches for engineering molecules with novel functions. These techniques are based on iterative amplification of
biopolymer libraries, interposed by selec
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