原创力文档the insect pathogen serratia marcescens db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin昆虫病原体粘质沙雷氏菌db10使用混合non-ribosomal肽synthetase-polyketide合酶生产抗生素异硫霉素.pdfVIP
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the insect pathogen serratia marcescens db10 uses a hybrid non-ribosomal peptide synthetase-polyketide synthase to produce the antibiotic althiomycin昆虫病原体粘质沙雷氏菌db10使用混合non-ribosomal肽synthetase-polyketide合酶生产抗生素异硫霉素
The Insect Pathogen Serratia marcescens Db10 Uses a
Hybrid Non-Ribosomal Peptide Synthetase-Polyketide
Synthase to Produce the Antibiotic Althiomycin
Amy J. Gerc1., Lijiang Song2., Gregory L. Challis2*, Nicola R. Stanley-Wall 1*, Sarah J. Coulthurst1 *
1 Division of Molecular Microbiology, College of Life Sciences, University of Dundee, Dundee, United Kingdom, 2 Department of Chemistry, University of Warwick,
Coventry, United Kingdom
Abstract
There is a continuing need to discover new bioactive natural products, such as antibiotics, in genetically-amenable
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