摄生肝泰胶囊对肝损伤动物治疗作用的实验研究（Experimental study on Shesheng Gantai Capsule on liver injury animal therapeutic effect）.doc

摄生肝泰胶囊对肝损伤动物治疗作用的实验研究（Experimental study on Shesheng Gantai Capsule on liver injury animal therapeutic effect） Experimental study on Shesheng Gantai Capsule on liver injury animal therapeutic effect Update: 2009-10-23 click on the Wu Yongjun Wang Xiaojuan Yu Rong Li Wen Guo Jiansheng Abstract: the middle and high dose Shesheng Gantai capsules can significantly inhibit the carbon tetrachloride (CC4) and D- amino galactose (D-Gla) in serum of mice with acute hepatic injury induced by alanine aminotransferase (ALT) and aspartate aminotransferase (AST) levels and total protein (TP) and albumin (ALB) drop, reduce the degree of the liver pathological damage. The higher dose Shesheng Gantai Capsule can inhibit the damage of ALT and AST in serum of rats with chronic liver induced by CCl4, TP and ALB decreased inhibition and liver tissue pathological damage, and can reduce the liver tissue hydroxyproline (HYP) content. It can enhance the nonspecific immune function and humoral immune function of mice with liver injury. Increase the amount of bile excretion and the content of bilirubin in the bile of normal rats. Key words: @ Shesheng Gantai Capsule / pharmacology; toxic hepatitis / chemically induced toxic hepatitis / drug therapy; Classification number: R258.5 Document identifier: A Shesheng Gantai Capsule is the experience of Mr. Li Peiran of Hunan province old TCM treatment of acute and chronic hepatitis in clinic, consisting of 12 herbs Astragalus, mulberry, Polygonum cuspidatum, Cyrtomium fortunei, with Invigorating Qi, detoxification effect. Report its pharmacodynamics action to be as follows now. 1 experimental materials 1.1 animals, NIH mice and SD rats were purchased from the experimental animal center of Hunan pharmaceutical industry research institute. 1.2 drug Shesheng Gantai Capsule, each g containing crude drug 6.7 g, Hunan Province Health Thai Industrial Co. company, batch number 940107, before use with distilled water suspension of corresponding concentration