注射用氨苄西林钠舒巴坦钠说明书（Ampicillin Sodium and Sulbactam Sodium for Injection manual）.docVIP

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注射用氨苄西林钠舒巴坦钠说明书（Ampicillin Sodium and Sulbactam Sodium for Injection manual）.doc

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注射用氨苄西林钠舒巴坦钠说明书（Ampicillin Sodium and Sulbactam Sodium for Injection manual）

注射用氨苄西林钠舒巴坦钠说明书（Ampicillin Sodium and Sulbactam Sodium for Injection manual） The common name of Ampicillin Sodium and Sulbactam Sodium for Injection Name used before English name AMPICILLIN, SODIUM, AND, SULBACTAM, SODIUM, FOR, LNJECTION Pinyin name ZHUSHEYONG, ANBIANXILINNA, SHUBATANNA Drug category penicillins Properties of this product are white or white powder or crystalline powder. Pharmacology and toxicology ampicillin sodium is a penicillin antibiotic. Chuba Staw Na (semi synthetic lactam enzyme inhibitor, on Neisseria gonorrhoeae, Neisseria meningitidis and Acinetobacter calcoaceticus have strong antibacterial activity to other bacteria are very poor, but the majority of Staphylococcus aureus and gram negative bacteria produced (lactamase inhibition of competition reversible strong. After the combination of two drugs, not only protects ampicillin from the hydrolysis of enzymes, but also expands its antibacterial spectrum. It also has good antibacterial activity against Staphylococcus producing enzymes, Acinetobacter and bacteroides. The product of Staphylococcus aureus, Streptococcus producing strains, including genera, pneumococcus, Enterococcus, Haemophilus influenzae, Moraxella Mora bacteria, Escherichia coli, Klebsiella, proteus, Bacillus Proteus, Neisseria gonorrhoeae, Clostridium, digestive ball bacteria, Peptostreptococcus and including b.fragilis genus Bacteroides, with antibacterial activity. After administration of ampicillin, 2G and sulbactam 1g, the peak concentration of serum (Cmax) was 109 to 150mg/L and 44 to 88mg/L, respectively. After intramuscular injection of ampicillin 1g and sulbactam 0.5g, the peak blood concentration (Cmax) was 8 to 37mg/L and 6 to 24mg/L, respectively. The blood elimination half-life (t1/2 ()) of the two drugs was about 1 hours. About 75% to 85% hours after the 8 hour administration, the urine is excreted through the prototype. The binding rate of ampicillin protein was 28%, and sulbactam was 38%. Both are well distri