贰型糖尿病患者脂代谢紊乱及其与血糖控制的关系（Lipid metabolism disorder and its relationship with glycemic control in patients with type 2 diabetes mellitus）.docVIP

贰型糖尿病患者脂代谢紊乱及其与血糖控制的关系（Lipid metabolism disorder and its relationship with glycemic control in patients with type 2 diabetes mellitus） Lipid metabolism disorder in type 2 diabetes mellitus and its relationship with glycemic control 2011-02-28 Liao Zhihong Yu Binjie 40% to 50% of patients with type 2 diabetes have abnormal lipid metabolism. Abnormal lipid metabolism is an important risk factor for coronary heart disease. The correction of hyperglycemia can improve the abnormality of lipid. We analyzed serum lipids between type 2 diabetes and healthy controls, and follow-up observation of changes of blood glucose and lipid in some patients, in order to further understand the degree of blood glucose control effect on blood lipid changes and influence. First, objects and methods 1. subjects: 291 cases (WHO diagnostic criteria) were randomly selected from the Department of Endocrinology, inpatient and specialist out-patient clinic in our hospital from 10 to 1994 January 1996. All patients had no liver or kidney disease, normal thyroid function, no acute metabolic disorder within 2 weeks, nor diuretics, lipid-lowering agents, antiplatelet agents, contraceptives, and other drugs that affected blood lipids. There were 102 males and 189 females, with an average age of 58 + 11 years. The average body mass index (BMI) was 23.6 + 4.2 kg/m2. With HbA1c = 6% for good glycemic control index in patients with type 2 diabetes, 85 cases of good glycemic control. 171 cases of non diabetic non coronary heart disease patients, the control group for our hospital staff and external units of cadres and workers of the physical examination of the crowd. Normal blood pressure, fasting blood glucose was less than 6.1mmol/L, without family history of diabetes; without chest discomfort and other symptoms of coronary artery disease and myocardial ischemia history, electrocardiogram examination was normal; normal function of liver and kidney; no abnormal thyroid function; without a family history o