1600例双能X线骨密度测定及诊断标准的探讨.pdfVIP

中国骨质疏橙杂志 1999年8月第5卷第3期 13 1600例双能X线骨密度测定及诊断标准的探讨 卓铁军 周明秀 申志祥 摘要 目的 了解本地区正常^腰椎、髋部各部位骨密度(BMD)随年龄变化 的规律和骨质疏松症(OP)BMD诊断标准探讨 方法 采用双能x线骨密度 仪测量15oo~E常^腰椎前后位、腰3侧位、股骨近段各部位BMD值，其中女 性1072例，男528倒，年龄范围3O～89岁，按l0岁一个年龄组分为6组统计分 折，同时分别以同性别、同部位峰值减低2 O及其2．5SD作为OP诊断标准进 行分析比较。结果 男女两性BMD值随年龄增长而下降．女性各部位BMD 下降趋势较男性明显，其中50~59岁和60～69岁两年龄组骨量呈快速丢失阶 段。两性骨丢失速度70岁之前Ward’sL LNeckTrocht 70岁之后 Ward’s》NeckTr0chL —I…在减低上0SD患病男性有28．8 t女性有35．1 的人已发生骨折 结论 为本地区不同性别、各年龄段BMD值及变化特点积累了数据和资料，同时提出为避免部分OP患者 误诊、漏谚．鉴于国情，OP诊断标准以减低2．0SD更合适。 关镑词 骨密度 骨质疏拾症 诊断 流性病学 Measurement of bone mineral density with DEXA in 1600 people and research on diagnostic criterion Zhuo Tiejun．Zhou Mingxiu tShen Zhixiang Jiangsu Provincial Geriatric Hospital，Nanjing 210024，China Abstract Objective To Study the change regularities of hone mineral density(BMD)of lumbar vertebra and femur with age in 1500 people and the diagnostic criterion of osteoporosis based on BMD． Method The BMD of the anterior posterior lumbar vertebra tthe laterior L3 and the proxlrrmI{emur were measured m 1072 females and 528 males．age ranging 30—89·They were divided into 6 groups by 10 years each and analyzed statistically by sex and site of bone according to the diagnostic criterion of OP of crease in BMD by mean minus 2．0 SD or 2．5 SD．Resell BMD declined with increasing age of both sexes，which was more noticeable n the female than in the male．and the bone loss was faster n age groups of 51—59 and 60 69．The rates of BMD loss were in the following order：Ward’sL 2一L