微生物降解苯甲酸的研究进展.PDFVIP

微生物学通报 DEC 20, 2012, 39(12): 1808−1816 Microbiology China © 2012 by Institute of Microbiology, CAS tongbao@ 专论与综述 微生物降解苯甲酸的研究进展 * 张晓云 盖忠辉 台萃 许平 (上海交通大学 微生物代谢国家重点实验室 上海 200240) 摘 要: 苯甲酸在工业中的广泛应用使其成为环境中的常见污染物, 对微生物好氧降解 苯甲酸的邻位途径、间位途径、龙胆酸途径和原儿茶酸途径及厌氧降解途径等进行总结, 并对苯甲酸降解过程中发挥重要作用的苯甲酸双加氧酶的种类、不同组分及苯甲酸降解 基因和调控基因的基因簇进行介绍, 同时展望微生物降解污染物的发展方向。 关键词: 苯甲酸, 降解途径, 双加氧酶, 基因簇 Advances in benzoic acid degradation by microorganism * ZHANG Xiao-Yun GAI Zhong-Hui TAI Cui XU Ping (State Key Laboratory of Microbial Metabolism, Shanghai Jiao Tong University, Shanghai 200240, China) Abstract: Benzoic acid is becoming a common pollutant in the environment because of its widely use in industry. We summarized different pathways of the aerobic and anaerobic deg- radation of benzoic acid by microorganism. Both the two- and three-component benzoic acid dioxygenases play important roles in the process of benzoic acid degradation. Gene clusters of benzoic acid degradation and regulation were introduced, and also the direction of pollution degradation by microorganism in the future. Keywords: Benzoic acid, Degradation pathway, Dioxygenase, Gene cluster 基金项目：上海交通大学综合交叉研究与培育专项 *通讯作者：Tel: 86-21 : ctai@ 收稿日期：2012-03-05; 接受日期：2012-05-03 张晓云等: 微生物降解苯甲酸的研究进展 1809 苯甲酸为无色、无味的片状晶体, 又被称为 物的微生物筛选和对这些化合物不同代谢途径 苯酸或安息香酸, 属于芳香族的弱酸, 在