单纯性乳房早发育向完全性中枢性性早熟转化的相关因素分析.pdfVIP

·174· 论 著 文章编号：1005—2224(2008)03-0174-03 单纯性乳房早发育向完全性中枢性 早熟转化的相关因素分析 朱顺叶1，杜敏联1，林爱华2 【摘要】 目的探讨单纯性乳房早发育(PI)向完全性中枢性性早熟(CCPP)转化的易患因素。方法纵向回 顾分析广州中山大学附属第一医院1995--2005年确诊为PT的151例惠儿临床及实验诊断资料。结果按转化 素暴露相关的子宫长径、乳房Tanner分期和乳房消退情况是转化的危险因素，以后两者的风险值最大。 【关键词】 中枢性性早熟；单纯性乳房早发育；相关因素 中图分类号：R72 文献标志码：A An ofriskfactorsfor thelarche into central ZHU completeprecociouspuberty． analysis prematureconverting First Min—lian-LIN ofPediatrics-theAffiliated Shun·ye，DU Ai·hua．Department HospitalofZhongshanUniversity，Guang- zhou 510080，China Abstract Todetecttheriskfactorsfor with into central Objective girls prematurethelarche(PT)convertingcomplete To the databasesoftheclinicalandsexualaxischaracteristicsin precociouspuberty(CCPP)．Methodsanalyfollow—up 151 withPT from1995to2005intheFirst AffiliatedtoSunYat=san Atotal girls diagnosed Hospital University．Results PT of with convertedintoCCPP．The of follow—up girlswere(7．07±0．65)yearsehronologi· 3l(20．5％)patientsduring cal ofbone whenidentifiedas convenedintoCCPP．69．5％ofthem ageand(8．97±1．12)yearsage having experienced ofbreast whom into recurrent completeregression development-offourteen(13．3％)convertedCCPP；20．5％had breast whom into constantbreast whomseven development-often(32．3％)convenedCCPP；9．9％had size-of into were differencesofthe rate thet