药理学-DrugsAffectingtheGastrointestinalSystem.pptVIP

Drugs Affecting the Gastrointestinal System 第一课件网 Drugs Affecting the Gastrointestinal System Antiulcerants Digestives Antiemetics Purgatives Antidiarrheals Cholagogues Peptic Ulcers Common disease，incidence rate: 10%~12%. Pathogenesis of ulcers Aggressive Factors Defensive Factors Acid,pepsin Bile salts Drugs (NSAIDs) H.pylori Mucus,bicarbonate layer Blood flow,cell renewal Prostaglandins Phospholipid Free radical scavengers Therapy Purpose： Therapy is directed at enhancing host defense or eliminating aggressive factors; i.e., H. pylori. Pepti