中西医结合治疗重型肝炎的荟萃分析.PDFVIP

10 201354 1000151 CNKI CBM-PubMed Stata 9.0 17 14924 P ALT350 U/L315 U/LSMD0.7195%CI 1.160.25 0.01 225 μmol/L147 μmol/LSMD0.88 95%CI 1.11 P 0.65 0.01 PTA39.28%20.96%SMD1.1995%CI 0.77 P 1.61 0.01 77.0%53.7% P RR1.4195%CI 1.311.52 0.01 40.7% P 22.4% RR1.8495%CI 1.502.26 0.01 Severe hepatitis treated by integrated traditional Chinese and Western medicine: a meta-analysis WANG Xiao-mei, WANG Xian-bo, LIU Hui-min (Beijing Ditan Hospital, Capital Medical University, Beijing 100015, China) Abstract: Objective A meta-analysis was conducted to evaluate the effi cacy of integrated traditional Chinese and Western medicine in the treatment of severe hepatitis. Methods Medical database including CNKI, CBM, Chinese scientifi c periodical full text database, Pubmed and Wanfang data were searched about treatment of severe hepatitis by the integrated Chinese and Western medicine, randomized controlled clinical trials (RCTs) comparing integrated Chinese and Western medicine with conventional Western medicine were screened out from the searched literatures, Stata 9.0 was used for the meta-analysis. The analysis included the calculation of standardized mean difference (SMD) for measurement data and odds ratio (OR) for enumeration data. Results Seventeen RCTs including 1492 cases were enrolled for analysis according to the eligibility and exclusion criteria. Compared to conventional Western treatment alone, the results of integrated traditional Chinese medicine and Western medicine treatment showed as follows: Decline of ALT in integrated treatment group (350 U/L) is grater than that in Western medicine group (315 U/L), SMD = 0.71, 95%CI 1.