糖尿病痛的性神经病变.ppt

Targets for Controlling Neuropathic Pain Now there are multiple neurotransmitters and different channels that mediate the electrical activity in the afferent pathways, and many of these are at least a potential target for controlling neuropathic pain. Gamma-aminobutyric acid (GABA) is an inhibitory neurotransmitter, and one would imagine that if one can increase inhibition in the pain pathways, you might reduce pain. Tackling GABA has been a bit disappointing, I must say, but it, at least, is a potential target for neuropathic pain. The sodium channels on the axons can also be blocked, reducin