睡眠剥夺对视觉短时记忆的脑电信息传输影响研究-现代仪器与医疗.pdfVIP

《现代仪器与医疗》 2014年  第20卷   第1期 论 著 睡眠剥夺对视觉短时记忆的脑电信息 传输影响研究 1 1 2 李宁 　张九妹 　刘锡禹 （1. 宁夏人民医院，银川　750001 ；2. 东软集团股份有限公司，沈阳　110179 ） [ 摘　要 ]　目的 ：睡眠剥夺（SD ）影响脑电波，基于脑电方法研究SD 对视觉刺激下的认知的 影响，建立一条评价大脑功能状态受到的影响的途径，探索睡眠对认知的作用机制。方法 ：在 正常状态下和一夜睡眠剥夺状态下，分别对10 名受试者进行视觉短时记忆测试，记录其多导 诱发脑电。通过计算各导联之间的互相干程度，研究SD 对大脑功能区域的同步化交互联系作用。 结果： SD 造成了大脑各功能区之间的关联程度下降，对大脑半球额叶间的关联影响较大。结论： 从脑电信号分析，睡眠剥夺对视觉短时记忆损害主要体现在对额叶影响上，引起记忆编码阶段 功能的降低。 [ 关键词 ]　睡眠剥夺；脑电；互相干；记忆 中图分类号：R741.02 B842　文献标识码：A　文章编号：2055-5200(2014)01-005-04 Doi：10.11876/mimt201401002 Research of EEG Features Induced by the Effects of Sleep Deprivation on Vision Short- term Memory LI Ning1 ZHANG Jiu-mei1 LIU Xi-yu2. 1. Ningxia People’s Hospital, 　 ， ， （ Yinchuan, 750001 2. Neusoft Corporation, Shenyang 110179 ； ） [Abstract]　Objective ：Sleep deprivation (SD) affects electroencephalography (EEG), by studying its effect on visual cognition based on EEG, we tried to establish a way to evaluate this kind of effect, and to investigate the mechanism underlying sleep regulation. Method: We finished experiments under two states including normal state and one night’s sleep deprived state. Evoked related potential of 10 volunteers were recorded during the visual short-term memory tests. By calculating cross coherence between leads, we studied the synchronous communication between cerebral cortex areas. Result: SD caused a decline of correlation between each functional area of brain, especially on the frontal lobes. Conclusion: By the analysis of EEG activity, SD affects the correlation between the frontal lobes on visual short-term memory, may reduce and function of encoding stage of memory. [Key words] Sleep deprivation EEG cross coherence memory 　 ； ； ； 前 言 回忆时也有感觉