TLR and Immunity最终版.pptVIP

* TLR and Immunity 2016.4.29 Introduction Structure Classification Function The roles in chronic inflammatory diseases OUTLINE 1、INTRODUCTION 1. Toll-like receptor(TLRs) are a group of pattern recognition receptors(PRRs),mainly expressed in Dentritic cells (DC) Macrophage plasmacytoid DC (pDC) 2. Participating innative immunity by pathogen-associated molecular patterns(PAMP). 3.TLR is also related to regulation of adaptive immunity. 1、INTRODUCTION 2、STRUCTURE 1. A kind of TypeⅠtransmembrane receptor 2. TLR cons