专业英语92.pptVIP

Nuclear export dynamics of RNA-protein complexes  主讲：王华飞，赵松辉 同组人：张雪朋，熊雪雪，蒲明辉， 杨吉团，杨宇 Nuclear export dynamics of RNA-protein complexes 1.Models of nucleocytoplasmic transport 2.Transport and single-molecule microscopy 3. Principles and players of messenger RNP export 4. The dynamics of mRNP export 5. Export of ribosomes and other RNAs 6. Outlook nucleocytoplasmic：核与质的 microscopy ：n. 显微镜检查；显微镜使用；显微镜学 . The central dogma of molecular biology— DNA makes RNA makes proteins — is a flow of information that in eukaryotes encounters a physical barrier: the nuclear envelope, which encapsulates, organizes and protects the genome. Nuclear-pore complexes, embedded in the nuclear envelope, regulate the passage of molecules to and from the nucleus, including the poorly understood process of the export of RNAs from the nucleus. encapsulate:[?n‘k?psj?le?t;] vt. 压缩；将…装入胶囊；将…封进内部 embedded in：嵌入 译：分子生物学的中心法则—DNA产生RNA产生蛋白质—是在真核细胞遇到能压缩，组织和保护基因组的核膜的物理屏障时的一种信息流。被嵌在核膜上的核孔复合体能调控通道分子进入和输出细胞核，包括难以被理解的RNA从核中运出的过程。 Recent imaging approaches focusing on single molecules have provide unexpected insight into this crucial step in the information flow. This review addresses the latest studies of RNA export and presents some models for how this complex process may work. 译：最近在信息流中对单分子成像方法的关注提供了对这关键一步的意想不到的洞察。这种观点表达了对RNA运出的最新研究并且为这种复杂的过程是如何进行的提供了一些模型。 The 100-nm diameter NPC has a core structure consisting of a hollow cylinder embedded in the nuclear envelope, which displays an eight-fold symmetry of about 30 different proteins termed nucleoporins (Nups). The NPC acts as the gateway between the nucleus and the cytoplasm; only those macromolecules carrying specific import and export signals are permitted to pass through the central channel of the NPC, although water and metabolites can pass through freely. cylinder: n. 圆筒；汽缸；[圆柱状物 symmetry: n.对称（性）；整齐，匀