胆囊切除术与大肠腺瘤的关系.pdfVIP

第 29 卷第 4 期 广 东 医 学 院 学 报 Vol. 29 No. 4 384 2011 年 8 月 JOURNAL OF GUANGDONG MEDICAL COLLEGE Aug. 2011 胆囊切除术与大肠腺瘤的关系分析 徐 永成，许岸 高，罗　程，陈惠新 （广东省惠州市 中心人 民医院消化 内科，广东惠州 5 1600 1） 摘　要： 目的 探讨胆囊切除术与大肠腺瘤发生 的关系。方法 回顾分析2008年至2010年在我院行全结肠镜检查 11 863例资料，以有胆囊切除术史的186例为研究组，按 1:3配比选择同时期相匹配的无胆囊切除术者558例为对照组，对两 组大肠腺瘤 的检 出率 、发生部位进行 比较 。结果 研究组 中检 出大肠腺瘤50例 (26.9%)，对照组 中检 出大肠腺瘤86例 (15.4%)，研究组 大肠腺瘤检 出率 明显 高于对 照组 (P0.05) 。研究组 和对 照组 近侧 大肠腺瘤所 占比例分别 为46.0%和 29.1%，远侧大肠腺瘤所 占比例分别为54.0%和70.9%，两组在大肠腺瘤发生部位方面存在差异 (P0.05)) 。结论 胆囊切 除可能增加大肠腺瘤发生的危险性。 关键词：胆囊切除术；大肠腺瘤；回顾性研究 中图分类号：R 575.6 文献标识码：A 文章编号：1005-4057(2011)04-0384-03 DOI: 10.3969/j.issn.1005-4057.2011.04.010 Relationship between cholecystectomy and colorectal adenoma XU Yong-cheng, XU An-gao, LUO Cheng, CHEN Hui-xin (Department of Gastroenterology, Huizhou Central Peoples Hospital, Huizhou 51600 1, China) Abstract: Objective To study the relationship between cholecystectomy and colorectal adenoma. Methods A total of 11 863 patients undergoing total colonoscopy were enrolled in our hospital between 2008 and 2010. Observation group included 186 patients with cholecystectomy, while control group included 558 patients without cholecystectomy. The detection rate and the location of colorectal adenoma were compared in two groups. Results The detection rate of colorectal adenoma was higher in observation group than that in control group (26.9% vs 15.4%, P0.05). The proportion of proximal colorectal adenoma in observation and control groups was 46.0% and 29.1%, whereas that of distal colorectal adenoma was 54.0% and 70.9%, respectively. The location difference of adenoma was significant between two groups (P0.05). Conclusion Cholecystectomy could increase the risk of colore